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• Activity deltas table
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Motif ID: TFAP2{A,C}.p2

Z-value: 2.919

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_45090025	8.951	NM_016932	SIX2	SIX homeobox 2
chr15_-_46724360	8.938		FBN1	fibrillin 1
chr17_+_52026058	8.562	NM_005450	NOG	noggin
chr8_-_80842452	8.154	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr3_+_51403760	7.984	NM_013286	RBM15B	RNA binding motif protein 15B
chr9_+_136673464	7.426	NM_000093	COL5A1	collagen, type V, alpha 1
chr9_+_136673534	6.876		COL5A1	collagen, type V, alpha 1
chr2_+_85834111	6.876	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr15_+_64782468	6.662		SMAD6	SMAD family member 6
chr16_+_85158357	6.482	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr3_-_126257425	6.298	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr5_-_159672060	6.218	NM_024565	CCNJL	cyclin J-like
chr10_+_23768203	6.138	NM_001145373	OTUD1	OTU domain containing 1
chr3_-_130807865	5.874	NM_015103	PLXND1	plexin D1
chr5_+_34692124	5.836	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr19_+_39664706	5.728	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr14_-_24588916	5.722	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr9_+_127549437	5.705	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr11_-_124175467	5.680		C11orf61	chromosome 11 open reading frame 61
chr4_+_108965167	5.583	NM_001136258	SGMS2	sphingomyelin synthase 2
chr12_-_105056577	5.458		NUAK1	NUAK family, SNF1-like kinase, 1
chr8_+_37672427	5.456	NM_025069	ZNF703	zinc finger protein 703
chr5_+_34692352	5.382	NM_001145520	RAI14	retinoic acid induced 14
chr2_+_36436873	5.368	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_+_92049396	5.334	NM_024832	RIN3	Ras and Rab interactor 3
chr2_-_37752272	5.318		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr16_-_71639670	5.274	NM_006885	ZFHX3	zinc finger homeobox 3
chr11_-_124175493	5.239	NM_024631	C11orf61	chromosome 11 open reading frame 61
chr2_-_236741352	5.159	NM_001485	GBX2	gastrulation brain homeobox 2
chr2_+_205118710	5.149	NM_057177 NM_152526 NM_205863	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr12_-_41269679	5.121	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr5_+_98132898	5.060	NM_001012761	RGMB	RGM domain family, member B
chr16_-_71650034	5.049	NM_001164766	ZFHX3	zinc finger homeobox 3
chrX_+_149282097	4.991	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr5_+_34692239	4.969		RAI14	retinoic acid induced 14
chr11_+_12652427	4.951	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_-_38666122	4.933	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr9_-_88751923	4.917	NM_002048	GAS1	growth arrest-specific 1
chr2_-_144991386	4.906		ZEB2	zinc finger E-box binding homeobox 2
chr4_-_140696740	4.850	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr9_+_98252200	4.766	NM_014282	HABP4	hyaluronan binding protein 4
chr19_+_15079141	4.765	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr2_+_241023908	4.739		GPC1	glypican 1
chr5_-_57791544	4.721	NM_006622	PLK2	polo-like kinase 2
chr1_-_68071635	4.719	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr1_-_32940943	4.697	NM_001161708 NM_030786	SYNC	syncoilin, intermediate filament protein
chr14_-_29466562	4.622	NM_002742	PRKD1	protein kinase D1
chr2_-_197165495	4.597	NM_020760	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr14_+_54102518	4.460		LOC644925	hypothetical LOC644925
chr16_+_52877009	4.422
chr10_-_49534304	4.376		ARHGAP22	Rho GTPase activating protein 22
chr15_-_53667800	4.362		PYGO1	pygopus homolog 1 (Drosophila)
chr3_+_160964574	4.357		SCHIP1	schwannomin interacting protein 1
chr1_-_32940850	4.326		SYNC	syncoilin, intermediate filament protein
chr2_+_205118961	4.307		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr5_+_14196287	4.301	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr2_+_241023880	4.266
chr2_+_205118801	4.223		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr9_-_37566248	4.211	NM_012166	FBXO10	F-box protein 10
chr5_-_172594691	4.165	NM_001166175 NM_001166176 NM_004387	NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)
chr1_-_85703198	4.157		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr10_-_35143900	4.139	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr3_+_173240983	4.134	NM_001135095	FNDC3B	fibronectin type III domain containing 3B
chr19_-_54557450	4.126	NM_003598	TEAD2	TEA domain family member 2
chr12_-_41164010	4.082		PRICKLE1	prickle homolog 1 (Drosophila)
chr2_+_241586927	4.041	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr16_-_52876390	4.016		IRX3	iroquois homeobox 3
chr8_-_48813256	4.013	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr4_-_141896920	4.007	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr1_-_6243621	3.991	NM_207370	GPR153	G protein-coupled receptor 153
chr2_-_144991556	3.975		ZEB2	zinc finger E-box binding homeobox 2
chr10_-_43464272	3.968	NM_006973	ZNF32	zinc finger protein 32
chr7_-_45927263	3.928	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chrX_-_34585287	3.917	NM_031442	TMEM47	transmembrane protein 47
chr3_+_148610516	3.902		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr10_+_123862430	3.893		TACC2	transforming, acidic coiled-coil containing protein 2
chr8_-_48813236	3.889		CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr14_+_51188289	3.879	NM_152330	FRMD6	FERM domain containing 6
chr12_+_52665196	3.834	NM_017409	HOXC10	homeobox C10
chrX_+_9943793	3.818	NM_015691	WWC3	WWC family member 3
chr3_+_171558188	3.817		SKIL	SKI-like oncogene
chr1_+_33494745	3.808	NM_152493	ZNF362	zinc finger protein 362
chr5_+_60663842	3.797	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr4_+_3434830	3.770	NM_001164673 NM_173660	DOK7	docking protein 7
chr2_+_36436316	3.750		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr16_-_52877467	3.689		IRX3	iroquois homeobox 3
chr13_+_109757593	3.677	NM_001846	COL4A2	collagen, type IV, alpha 2
chr2_+_235525355	3.632	NM_014521	SH3BP4	SH3-domain binding protein 4
chr12_-_105165805	3.630	NM_006825	CKAP4	cytoskeleton-associated protein 4
chrX_-_54538591	3.621		FGD1	FYVE, RhoGEF and PH domain containing 1
chr9_-_72218098	3.618		KLF9	Kruppel-like factor 9
chr10_-_88271466	3.606		WAPAL	wings apart-like homolog (Drosophila)
chr1_+_143920424	3.598	NM_203458	NOTCH2NL	notch 2 N-terminal like
chr12_+_66328760	3.575	NM_003583 NM_006482	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr7_+_27190688	3.574
chr1_-_39877883	3.565		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr10_+_116571485	3.561	NM_001135051 NM_020940	FAM160B1	family with sequence similarity 160, member B1
chr15_+_65145215	3.559		SMAD3	SMAD family member 3
chr19_+_16296632	3.555	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr14_-_102593384	3.554	NM_006035	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)
chr1_-_39877928	3.543	NM_014571	HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr13_-_73606362	3.540		KLF12	Kruppel-like factor 12
chr1_-_95165037	3.522		CNN3	calponin 3, acidic
chr18_+_18969724	3.517	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr5_+_72957736	3.514	NM_001080479 NM_001177693	RGNEF	190 kDa guanine nucleotide exchange factor
chr12_-_41164052	3.507	NM_001144882 NM_001144883	PRICKLE1	prickle homolog 1 (Drosophila)
chr10_+_104394185	3.493	NM_030912	TRIM8	tripartite motif containing 8
chr9_-_135847106	3.488	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr2_+_159533329	3.430	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr8_+_22479115	3.424	NM_001018003	SORBS3	sorbin and SH3 domain containing 3
chr1_-_212791467	3.419		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr9_-_83493415	3.414	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr6_-_132314004	3.409	NM_001901	CTGF	connective tissue growth factor
chr6_-_128883125	3.369	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr17_-_72218661	3.359		MXRA7	matrix-remodelling associated 7
chr3_-_151171576	3.341		PFN2	profilin 2
chr21_-_27139143	3.337		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr7_-_150576660	3.321	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_60954096	3.296		SDHAF2	succinate dehydrogenase complex assembly factor 2
chr21_+_36993860	3.280	NM_005069 NM_009586	SIM2	single-minded homolog 2 (Drosophila)
chr9_+_81377419	3.264		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr17_+_35751796	3.257	NM_001024809	RARA	retinoic acid receptor, alpha
chr1_+_179148935	3.238	NM_020950	KIAA1614	KIAA1614
chr10_-_101370147	3.235		SLC25A28	solute carrier family 25, member 28
chr3_+_49002774	3.231		P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr20_+_11819364	3.214	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr13_-_109757442	3.214	NM_001845	COL4A1	collagen, type IV, alpha 1
chr9_-_25668230	3.201		TUSC1	tumor suppressor candidate 1
chr3_-_151171190	3.184	NM_002628 NM_053024	PFN2	profilin 2
chr10_-_101370207	3.173	NM_031212	SLC25A28	solute carrier family 25, member 28
chr10_+_42953886	3.167	NM_018590	CSGALNACT2	chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr3_+_171558215	3.160		SKIL	SKI-like oncogene
chr10_-_131652364	3.155		EBF3	early B-cell factor 3
chr3_+_44878380	3.100	NM_144638	TMEM42	transmembrane protein 42
chr2_+_241023703	3.092	NM_002081	GPC1	glypican 1
chr10_+_124124196	3.083		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_-_175255717	3.061	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr11_+_32068990	3.055	NM_002901	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr4_-_158111995	3.050	NM_016205	PDGFC	platelet derived growth factor C
chr12_-_75796898	3.044	NM_001321	CSRP2	cysteine and glycine-rich protein 2
chr17_-_72218535	3.039	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr4_+_151218862	3.031	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr16_+_82490230	3.022	NM_012213	MLYCD	malonyl-CoA decarboxylase
chr18_+_32131628	3.019	NM_025135	FHOD3	formin homology 2 domain containing 3
chr11_+_72697310	3.019	NM_014786	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17
chr22_+_29361672	3.015	NM_001001479	SLC35E4	solute carrier family 35, member E4
chr15_-_81667169	3.010	NM_016073	HDGFRP3	hepatoma-derived growth factor, related protein 3
chr9_-_122516399	3.002	NM_001080497	MEGF9	multiple EGF-like-domains 9
chr7_+_90731671	3.001	NM_003505	FZD1	frizzled homolog 1 (Drosophila)
chr10_-_131652007	2.999	NM_001005463	EBF3	early B-cell factor 3
chr12_-_104153920	2.999	NM_018171	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr6_+_151229003	2.998		MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr1_-_36562341	2.988	NM_018166	FAM176B	family with sequence similarity 176, member B
chr11_+_19691397	2.984	NM_145117 NM_182964	NAV2	neuron navigator 2
chr5_+_129268352	2.978	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr6_+_151228757	2.968		MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr3_-_121652183	2.966	NM_007085	FSTL1	follistatin-like 1
chr12_-_46499834	2.962	NM_001098416 NM_015401	HDAC7	histone deacetylase 7
chr1_+_39647762	2.951	NM_015038	KIAA0754	KIAA0754
chr5_-_172688024	2.938		STC2	stanniocalcin 2
chr20_-_43953036	2.938	NM_080749	NEURL2	neuralized homolog 2 (Drosophila)
chr15_+_65145248	2.937	NM_005902	SMAD3	SMAD family member 3
chr5_+_53849396	2.935		SNX18	sorting nexin 18
chr3_-_130517759	2.914	NM_006026	H1FX	H1 histone family, member X
chr1_-_222100226	2.909		TP53BP2	tumor protein p53 binding protein, 2
chr7_-_526005	2.900	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr19_-_1799447	2.892	NM_020695	REXO1	REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr15_-_46725087	2.891	NM_000138	FBN1	fibrillin 1
chr1_-_158091296	2.891		C1orf204	chromosome 1 open reading frame 204
chr1_-_120413698	2.885		NOTCH2	notch 2
chr20_+_43952997	2.877	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr13_+_30378311	2.872	NM_032849	C13orf33	chromosome 13 open reading frame 33
chr19_+_1200882	2.864		MIDN	midnolin
chr3_+_49002285	2.860	NM_177938 NM_177939	P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr13_-_76358370	2.859		KCTD12	potassium channel tetramerisation domain containing 12
chr10_-_101370076	2.852		SLC25A28	solute carrier family 25, member 28
chr5_+_149845503	2.852		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr10_+_11824361	2.846	NM_024693	ECHDC3	enoyl CoA hydratase domain containing 3
chr1_+_52380633	2.840	NM_004799 NM_007323 NM_007324	ZFYVE9	zinc finger, FYVE domain containing 9
chr12_+_26239755	2.831	NM_005086	SSPN	sarcospan (Kras oncogene-associated gene)
chr10_-_118491971	2.825	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr9_+_81377289	2.818		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr21_+_45318861	2.816	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr18_-_12647736	2.814		SPIRE1	spire homolog 1 (Drosophila)
chr2_-_160972606	2.811		RBMS1	RNA binding motif, single stranded interacting protein 1
chr22_+_36286350	2.807	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr1_+_6767968	2.805	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr7_-_525556	2.796		PDGFA	platelet-derived growth factor alpha polypeptide
chr5_-_38592439	2.794	NM_001127671	LIFR	leukemia inhibitory factor receptor alpha
chr22_-_28972683	2.794	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr12_-_78608154	2.777		PAWR	PRKC, apoptosis, WT1, regulator
chr6_+_3696224	2.774
chr11_+_72696963	2.759		ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17
chr17_-_34209671	2.751	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr4_+_37655385	2.751		TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr14_-_102593264	2.741
chr16_+_88517187	2.723	NM_006086	TUBB3	tubulin, beta 3
chr1_+_10193267	2.722	NM_015074 NM_183416	KIF1B	kinesin family member 1B
chr6_-_105734535	2.721	NM_022361	POPDC3	popeye domain containing 3
chr7_-_27190882	2.714		HOXA11	homeobox A11

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	9.24e-39	GO:0009987	cellular process
1.21	1.01e-33	GO:0044260	cellular macromolecule metabolic process
1.16	2.36e-33	GO:0044237	cellular metabolic process
1.14	5.51e-30	GO:0008152	metabolic process
1.15	1.08e-27	GO:0044238	primary metabolic process
1.17	1.08e-25	GO:0043170	macromolecule metabolic process
1.23	1.65e-22	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	4.23e-18	GO:0034641	cellular nitrogen compound metabolic process
1.22	7.97e-18	GO:0071842	cellular component organization at cellular level
1.19	1.05e-17	GO:0006807	nitrogen compound metabolic process
1.23	3.74e-17	GO:0090304	nucleic acid metabolic process
1.21	7.19e-17	GO:0071841	cellular component organization or biogenesis at cellular level
1.11	2.02e-16	GO:0050794	regulation of cellular process
1.21	1.88e-15	GO:0044267	cellular protein metabolic process
1.26	3.08e-15	GO:0006996	organelle organization
1.17	3.18e-15	GO:0016043	cellular component organization
1.10	2.22e-14	GO:0050789	regulation of biological process
1.09	2.36e-14	GO:0065007	biological regulation
1.16	4.21e-14	GO:0071840	cellular component organization or biogenesis
1.23	1.56e-12	GO:0010467	gene expression
1.23	2.64e-12	GO:0016070	RNA metabolic process
1.19	9.34e-11	GO:0048523	negative regulation of cellular process
1.29	9.94e-11	GO:0007049	cell cycle
1.18	1.61e-10	GO:0048519	negative regulation of biological process
1.37	2.12e-10	GO:0051726	regulation of cell cycle
1.17	9.85e-10	GO:0044249	cellular biosynthetic process
1.15	1.14e-09	GO:0019538	protein metabolic process
1.17	1.45e-09	GO:0048522	positive regulation of cellular process
1.17	1.52e-09	GO:0009058	biosynthetic process
1.36	2.82e-09	GO:0000278	mitotic cell cycle
1.21	4.72e-09	GO:0009059	macromolecule biosynthetic process
1.21	6.02e-09	GO:0034645	cellular macromolecule biosynthetic process
1.16	1.08e-08	GO:0048518	positive regulation of biological process
1.19	1.44e-08	GO:0006464	protein modification process
1.18	3.00e-08	GO:0043412	macromolecule modification
1.29	7.28e-08	GO:0022402	cell cycle process
1.45	1.88e-07	GO:0051325	interphase
1.19	3.41e-07	GO:0023051	regulation of signaling
1.23	3.41e-07	GO:0044248	cellular catabolic process
1.45	5.72e-07	GO:0051329	interphase of mitotic cell cycle
1.20	6.79e-07	GO:0009966	regulation of signal transduction
1.34	8.03e-07	GO:0016071	mRNA metabolic process
1.12	1.27e-06	GO:0031323	regulation of cellular metabolic process
1.11	2.99e-06	GO:0019222	regulation of metabolic process
1.28	3.98e-06	GO:0022403	cell cycle phase
1.30	6.54e-06	GO:0051276	chromosome organization
1.37	1.15e-05	GO:0006397	mRNA processing
1.38	1.55e-05	GO:0044419	interspecies interaction between organisms
1.18	1.75e-05	GO:0007399	nervous system development
1.21	2.38e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.11	2.59e-05	GO:0080090	regulation of primary metabolic process
1.31	3.37e-05	GO:0044265	cellular macromolecule catabolic process
1.20	4.08e-05	GO:0031325	positive regulation of cellular metabolic process
1.21	5.13e-05	GO:0042981	regulation of apoptosis
1.37	5.64e-05	GO:0010564	regulation of cell cycle process
1.28	6.80e-05	GO:0009057	macromolecule catabolic process
1.21	6.88e-05	GO:0010941	regulation of cell death
1.23	7.47e-05	GO:0022008	neurogenesis
1.18	7.57e-05	GO:0009056	catabolic process
1.19	9.11e-05	GO:0009893	positive regulation of metabolic process
1.19	9.40e-05	GO:0051641	cellular localization
1.24	1.00e-04	GO:0051128	regulation of cellular component organization
1.21	1.01e-04	GO:0043067	regulation of programmed cell death
1.21	1.11e-04	GO:0032268	regulation of cellular protein metabolic process
1.26	2.30e-04	GO:0006396	RNA processing
1.23	2.58e-04	GO:0033554	cellular response to stress
1.11	2.62e-04	GO:0060255	regulation of macromolecule metabolic process
1.30	2.67e-04	GO:0007010	cytoskeleton organization
1.22	3.62e-04	GO:0048699	generation of neurons
1.15	3.84e-04	GO:0048583	regulation of response to stimulus
1.30	3.98e-04	GO:0006325	chromatin organization
1.22	4.45e-04	GO:0006351	transcription, DNA-dependent
1.29	5.78e-04	GO:0000904	cell morphogenesis involved in differentiation
1.17	6.04e-04	GO:0035556	intracellular signal transduction
1.36	7.23e-04	GO:0008380	RNA splicing
1.26	7.25e-04	GO:0006259	DNA metabolic process
1.41	7.83e-04	GO:0051129	negative regulation of cellular component organization
1.21	9.83e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.19	9.95e-04	GO:0051246	regulation of protein metabolic process
1.20	1.03e-03	GO:0032774	RNA biosynthetic process
1.23	1.33e-03	GO:0071844	cellular component assembly at cellular level
1.26	1.41e-03	GO:0000902	cell morphogenesis
1.79	1.52e-03	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
1.32	1.57e-03	GO:0016568	chromatin modification
1.27	1.74e-03	GO:0006974	response to DNA damage stimulus
1.23	2.14e-03	GO:0012501	programmed cell death
1.19	2.20e-03	GO:0009892	negative regulation of metabolic process
1.24	2.29e-03	GO:0030030	cell projection organization
1.20	2.35e-03	GO:0031324	negative regulation of cellular metabolic process
1.24	2.50e-03	GO:0032989	cellular component morphogenesis
1.32	2.93e-03	GO:0051301	cell division
1.41	3.02e-03	GO:0045786	negative regulation of cell cycle
1.18	3.08e-03	GO:0008104	protein localization
1.40	3.14e-03	GO:0071156	regulation of cell cycle arrest
1.38	3.44e-03	GO:0030036	actin cytoskeleton organization
1.21	3.61e-03	GO:0046907	intracellular transport
1.09	3.61e-03	GO:0051716	cellular response to stimulus
1.22	3.61e-03	GO:0006915	apoptosis
1.20	3.79e-03	GO:0048468	cell development
1.49	3.82e-03	GO:0000082	G1/S transition of mitotic cell cycle
1.21	4.11e-03	GO:0031399	regulation of protein modification process
1.20	4.69e-03	GO:0008219	cell death
1.35	4.78e-03	GO:0030029	actin filament-based process
1.20	6.41e-03	GO:0016265	death
1.29	6.55e-03	GO:0051247	positive regulation of protein metabolic process
1.16	6.86e-03	GO:0033036	macromolecule localization
1.32	7.44e-03	GO:0009894	regulation of catabolic process
1.33	8.09e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.25	8.55e-03	GO:0010942	positive regulation of cell death
1.18	9.89e-03	GO:0022607	cellular component assembly
1.32	1.03e-02	GO:0033043	regulation of organelle organization
1.40	1.14e-02	GO:0000375	RNA splicing, via transesterification reactions
1.30	1.17e-02	GO:0018193	peptidyl-amino acid modification
1.25	1.20e-02	GO:0043065	positive regulation of apoptosis
1.25	1.46e-02	GO:0043068	positive regulation of programmed cell death
1.53	1.50e-02	GO:0031398	positive regulation of protein ubiquitination
1.29	1.59e-02	GO:0007264	small GTPase mediated signal transduction
1.17	1.60e-02	GO:0051649	establishment of localization in cell
1.29	1.61e-02	GO:0032270	positive regulation of cellular protein metabolic process
1.29	1.77e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.17	1.82e-02	GO:0010646	regulation of cell communication
1.08	1.89e-02	GO:0032502	developmental process
1.23	2.20e-02	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.21	2.20e-02	GO:0030182	neuron differentiation
1.37	2.36e-02	GO:0000075	cell cycle checkpoint
1.35	2.36e-02	GO:0046578	regulation of Ras protein signal transduction
1.31	2.40e-02	GO:0019941	modification-dependent protein catabolic process
1.18	2.54e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.17	2.83e-02	GO:0006793	phosphorus metabolic process
1.17	2.83e-02	GO:0006796	phosphate metabolic process
1.21	2.98e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.38	3.15e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.38	3.15e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
1.21	3.30e-02	GO:0009890	negative regulation of biosynthetic process
1.32	3.70e-02	GO:0031329	regulation of cellular catabolic process
1.29	3.73e-02	GO:0044257	cellular protein catabolic process
1.30	3.89e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.30	4.06e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.12	4.27e-02	GO:0044281	small molecule metabolic process
1.10	4.40e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.14	4.55e-02	GO:0065009	regulation of molecular function
1.26	4.61e-02	GO:0048667	cell morphogenesis involved in neuron differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	3.68e-68	GO:0005622	intracellular
1.12	1.23e-67	GO:0044424	intracellular part
1.13	1.40e-48	GO:0043226	organelle
1.13	6.62e-48	GO:0043229	intracellular organelle
1.14	1.55e-46	GO:0043227	membrane-bounded organelle
1.14	6.65e-46	GO:0043231	intracellular membrane-bounded organelle
1.14	2.01e-43	GO:0005737	cytoplasm
1.16	3.93e-30	GO:0044444	cytoplasmic part
1.16	2.23e-29	GO:0044446	intracellular organelle part
1.16	3.82e-29	GO:0044422	organelle part
1.16	9.13e-28	GO:0005634	nucleus
1.25	3.10e-21	GO:0044428	nuclear part
1.24	1.76e-18	GO:0005829	cytosol
1.22	1.41e-16	GO:0070013	intracellular organelle lumen
1.21	2.98e-16	GO:0031974	membrane-enclosed lumen
1.21	4.07e-16	GO:0043233	organelle lumen
1.24	4.78e-16	GO:0031981	nuclear lumen
1.15	1.30e-12	GO:0032991	macromolecular complex
1.25	1.34e-11	GO:0005654	nucleoplasm
1.03	2.75e-10	GO:0005623	cell
1.03	3.37e-10	GO:0044464	cell part
1.15	1.67e-09	GO:0043228	non-membrane-bounded organelle
1.15	1.67e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.14	4.34e-09	GO:0043234	protein complex
1.20	1.99e-08	GO:0012505	endomembrane system
1.16	5.97e-08	GO:0031090	organelle membrane
1.27	5.61e-05	GO:0005694	chromosome
1.23	8.23e-05	GO:0044451	nucleoplasm part
1.46	1.02e-04	GO:0031252	cell leading edge
1.23	1.52e-04	GO:0031967	organelle envelope
1.22	2.96e-04	GO:0031975	envelope
1.28	4.10e-04	GO:0044427	chromosomal part
1.14	7.87e-04	GO:0005856	cytoskeleton
1.18	8.91e-04	GO:0005794	Golgi apparatus
1.35	2.48e-03	GO:0005635	nuclear envelope
1.21	2.57e-03	GO:0015630	microtubule cytoskeleton
1.22	4.16e-03	GO:0044431	Golgi apparatus part
1.56	4.52e-03	GO:0042470	melanosome
1.56	4.52e-03	GO:0048770	pigment granule
1.18	6.93e-03	GO:0031982	vesicle
1.42	1.03e-02	GO:0031965	nuclear membrane
1.99	1.07e-02	GO:0032154	cleavage furrow
1.14	1.26e-02	GO:0005739	mitochondrion
1.18	1.31e-02	GO:0031410	cytoplasmic vesicle
1.19	1.37e-02	GO:0031988	membrane-bounded vesicle
1.41	1.52e-02	GO:0005912	adherens junction
1.22	1.55e-02	GO:0005730	nucleolus
1.55	2.17e-02	GO:0014069	postsynaptic density
1.18	2.65e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.48	2.67e-02	GO:0005795	Golgi stack
1.26	2.69e-02	GO:0005815	microtubule organizing center
1.14	3.10e-02	GO:0005783	endoplasmic reticulum
1.55	3.14e-02	GO:0031985	Golgi cisterna
1.37	3.21e-02	GO:0070161	anchoring junction
1.54	3.39e-02	GO:0031984	organelle subcompartment
1.21	3.62e-02	GO:0030529	ribonucleoprotein complex
1.28	3.97e-02	GO:0015629	actin cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	3.82e-42	GO:0005515	protein binding
1.07	3.20e-27	GO:0005488	binding
1.11	5.80e-11	GO:0003824	catalytic activity
1.17	1.56e-09	GO:0000166	nucleotide binding
1.37	9.94e-08	GO:0019904	protein domain specific binding
1.28	1.21e-07	GO:0019899	enzyme binding
1.16	3.44e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.16	4.33e-06	GO:0017076	purine nucleotide binding
1.16	4.96e-06	GO:0032553	ribonucleotide binding
1.16	4.96e-06	GO:0032555	purine ribonucleotide binding
1.31	1.59e-05	GO:0030695	GTPase regulator activity
1.11	2.17e-05	GO:0003676	nucleic acid binding
1.17	2.23e-05	GO:0005524	ATP binding
1.17	2.81e-05	GO:0030554	adenyl nucleotide binding
1.17	3.13e-05	GO:0032559	adenyl ribonucleotide binding
1.30	4.40e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.20	9.33e-05	GO:0030528	transcription regulator activity
1.15	1.35e-04	GO:0016740	transferase activity
1.88	5.37e-04	GO:0046332	SMAD binding
1.19	9.05e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.12	1.38e-03	GO:0003677	DNA binding
1.25	1.59e-03	GO:0008092	cytoskeletal protein binding
1.33	2.41e-03	GO:0005083	small GTPase regulator activity
1.20	3.98e-03	GO:0016301	kinase activity
1.17	7.29e-03	GO:0030234	enzyme regulator activity
1.24	2.18e-02	GO:0004674	protein serine/threonine kinase activity
1.28	2.37e-02	GO:0016563	transcription activator activity
2.35	2.48e-02	GO:0070412	R-SMAD binding
1.27	3.71e-02	GO:0003779	actin binding
1.18	4.30e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.55	4.31e-02	GO:0031625	ubiquitin protein ligase binding
1.45	4.45e-02	GO:0051020	GTPase binding